Lamborghini: American Challenge is a racing game where players start with a basic Lamborghini and $6000, competing across 60 tracks in the United States to advance through four racing divisions. Players race against championship rivals and local drivers while avoiding police who pursue speeders exceeding 110 km/h, attempting to ram offenders off the road. The game features a betting system where players wager on race outcomes against other championship drivers, and progression requires completing Divisional Challenge time trials. Players can purchase upgrades including tires, radar jammers, engine improvements, and nitro boosts using race earnings, with each race requiring an entry fee and offering monetary rewards based on performance and successful bets.